Our History 

Since 1947, we have produced medicines for the Public Health System of the Argentinean province, Santa Fe. Towards the end of the 1940’s the Argentinean National Government created the Secretariat of Public Health entrusting Dr. Ramón Carrillo with the Secretary position, and he later became the first Ministry of Health in Argentina’s history. In that context, the creation of Hospital Pharmacies was promoted as an alternative solution to the needs of medicines from the Public Health System.

In line with the situation, the province of Santa Fe implemented the needed actions for the installation of a medicine production unit, with the objective of supplying those recently created Hospital Pharmacies. That medicines production unit was called Laboratorio Industrial Farmacéutico, or its acronym LIF (Pharmaceutical Industrial Laboratory, in English), which coincides with the current name.

Although there are no official records of its creation, LIF continued to work under that name until 1987, year in which the Provincial Legislature finally sanctioned Law No. 10 069, officially creating ‘Laboratorio Productor de Fármacos Medicinales’ or its acronym LFPM (Medicine Producer Laboratory, in English).

In 1989, the laboratory ceased to be a Division of the Supply Management of the Health Ministry and became the General Directorate of Medicines Production. During that period, important investments on equipment and infrastructure were made establishing an adequate profile for the industrial demands.
Consequently, the laboratory began to play a leading role providing medicines to the Ministry of Health of Santa Fe.

At the beginning of the 1990s, the Public Health System became more complex and the LIF needed to fulfill the recently updated national regulatory framework to provide a quick and effective response to the Public Health patients.

In 1999, Provincial Law No. 11 657 transformed LPFM into a state-owned enterprise (SE, acronym in Spanish), in order to provide suitable responses to Public Health demands.

As a result, LPFM SE became an undisputed national referent among the constellation of Argentinean state-owned laboratories of medicines production. Additionally, it had a very well known recognition of the national health authorities.

Finally, in 2007, the last change took place and the organization returned to its original name: Laboratorio Industrial Farmacéutico; but this time being a state-owned enterprise, Sociedad de Estado (LIF SE). One year later, LIF SE achieved the commercial authorization from the National Food, Drug and Medical Technology Administration (Administración Nacional de Medicamentos, Alimentos y Tecnología Médica, ANMAT) and we became one of the first public medicines producer to provide to the largest National Health Program for medicine supply called REMEDIAR. This participation expanded our horizons and our products reached all Argentine provinces.


Currently, throughout the provincial territory we are supplying the Primary Health Care System of Santa Fe with our production. Monthly, we reach 795 healthcare providers of the 5 regions that make Santa Fe ‘s Health System: Rafaela, Reconquista, Rosario, Santa Fe and Venado Tuerto. In addition, we directly supply major hospitals such as CEMAFE, Alassia, Cullen, Iturraspe, Mira y López and Sayago in Santa Fe city, and Centenario, Eva Perón and Hospital Provincial in Rosario.

We maintain our growth through continuous investment in training for our professional team, in infrastructure and in technological innovations. Furthermore, in the constant exchange with the scientific-technological ecosystem at regional and national level.

 Strategic Plan 

 Authorities / Board of Directors 


Our production is distributed free of charge through the Public Health System of Santa Fe. Moreover, the products that have national certificates (ANMAT cert.) can reach all Argentine provinces.


  • Amoxicillin 500 mg – ANMAT Cert. Nº 54.603
  • Cephalexin 500 mg – ANMAT Cert. Nº 54.328
  • Amoxicillin 250 mg / 5 ml susp. x 90 ml – ANMAT Cert. Nº 52.296
  • Amoxicillin 500 mg / 5 ml susp. x 90 ml – ANMAT Cert. Nº 52.296
  • Cephalexin 250 / 5 ml susp. x 90 ml – ANMAT Cert. Nº 52.314
  • Cephalexin 500 mg / 5 ml susp. x 90 ml – ANMAT Cert. Nº 52.314
  • Azithromycin 500 mg
  • Clarithromycin 500 mg
  • Gentamicin 0,3% x 10 ml
  • Cotrimoxazole 400 / 80 mg


  • Atenolol 100 mg – ANMAT Cert. Nº 54.599
  • Enalapril Maleate 10 mg – ANMAT Cert. Nº 54.922
  • Losartan 50 mg


  • Hyoscine Butylbromide 10 mg – ANMAT Cert. Nº 54.049

Antiparasitic Opioid

  • Mebendazole 100 mg – ANMAT Cert. No 55.776


  • Morphine 10 mg – ANMAT Cert. Nº 57.439
  • Methadone 5 mg – ANMAT Cert. Nº 57.473
  • Methadone 10 mg – ANMAT Cert. Nº 57.473
  • Morphine 0,2% (Syrup)

Uterotonic Agents

  • Misoprostol 200 mcg Vaginal Tablets – ANMAT Cert. Nº 59.391
  • Misoprostol 200 mcg Oral Tablets


  • Mifepristone 200 mg


  • Paracetamol 500 mg – ANMAT Cert. Nº 54.235
  • Ibuprofen 400 mg – ANMAT Cert. Nº 55.576
  • Ibuprofen 2 % susp. x 90 ml


  • Dexamethasone 0,5 mg
  • Dexamethasone 8 mg / 2 ml (inj.)


  • Metformin 500 mg – ANMAT Cert. Nº 54.180
  • Gliclazide 30 mg
  • Metformin 850 mg ER

Lipid-lowering medicines

  • Simvastatin 20 mg – ANMAT Cert. Nº 54.487
  • Atorvastatin 20 mg


  • Haloperidol 1 mg
  • Haloperidol 5 mg


  • Ethambutol 400 mg
  • Isoniazid 100 mg
  • Isoniazid 300 mg
  • Rifampicin 150 mg + Isoniazid 75 mg + Pyrazinamide 400 mg
  • Rifampicin 300 mg + Isoniazid 150 mg


  • Permethrin 2,75% (cream)


  • Permethrin 5% (cream)

Oral Contraceptive

  • Levonorgestrel 0,15 mg / Etinyl estradiol 0,03 mg – ANMAT Cert. Nº 57.213


  • Repellent LIF 145 ml (spray for external use)


  • Sunscreen LIF 70 gr SPF 50+ (cream for external use)


  • Alcohol gel 1L, 500 ml, 100 ml


  • Cannabis oil CBD 10% w/v (100 mg / 1 ml)


One of the objectives of LIF SE is to provide medicines to the Public Health System in order to contribute to the achievement of health sovereignty. Due to the work of our researchers and developers, the number of medicines we offer to patients of public health increases every year.
During the current management of LIF SE, we have incorporated 14 new products to our portfolio:

  • Metformin 850 mg ER
  • Mifepristone 200 mg
  • Dexamethasone 0 5 mg
  • Sunscreen LIF 70 gr SPF 50+ (cream for external use)
  • Cannabis oil CBD 10% w/v (100 mg / 1 ml)
  • Alcohol gel 1L, 500 ml, 100 ml
  • Atorvastatin 20 mg
  • Azithromycin 500 mg
  • Clarithromycin 500 mg
  • Gliclazide 30 mg
  • Losartan 50 mg
  • Misoprostol 200 mcg Vaginal Tablets
  • Misoprostol 200 mcg Oral Tablets
  • Repellent LIF 145 ml